Table 2.

Baseline values in WT and Sglt2^−/− mice

Genotype	Blood glucose, mg/dL	Urinary glucose, µmol/mg creatinine	FE-glucose, %	Body weight, g	Hematocrit, %	Plasma creatinine, mg/dL	Urine osmolality, mosm/kg	Plasma osmolality, mosm/kg
WT	151 ± 5	8.0 ± 0.6	0.10 ± 0.01	27.3 ± 0.7	43.1 ± 0.4	0.105 ± 0.002	1,736 ± 91	284 ± 3.3
Sglt2−/−	122 ± 5*	1,581 ± 124*	26.2 ± 2.3*	25.1 ± 0.4*	44.7 ± 0.4*	0.115 ± 0.004 (P = 0.058)	1,455 ± 42*	293 ± 3.5 (P = 0.079)

Results are means ± SE; n = 14–18 mice/group. Baseline data were not significantly different between sham-operated and ischemia-reperfused groups for a given genotype and thus were pooled. WT, wild type; Sglt2^−/−, Na⁺-glucose transporter 2 knockout; FE-glucose, fractional renal excretion of glucose.

^*P < 0.05 vs. WT mice using an unpaired t test.