Fig. 5.

Expression of senescence-associated secretory phenotype factors in murine kidneys after transplantation of control or senescent (SEN) renal scattered tubular-like cells (STCs). A: gene expression of senescence-associated secretory phenotype factors quantified by RT-PCR (relative to GAPDH). Values are means ± SD; n = 5 in the control group and n = 6 in the SEN group. ▲, male; ●, female. *P < 0.05 vs. the control group by Student’s t tests. B: representative immunofluorescence of prelabeled transplanted renal STCs (red) colocalizing (yellow) with IL-6 staining (green, arrow) in the kidney. DAPI is shown in blue. Il6, interleukin-6; Ccl2, chemokine (C-C motif) ligand 2; Serpine1, serpin family E member 1; Tnfa, tumor necrosis factor-α; Vegf, vascular endothelial growth factor.