Table 3.
Sleep–wake rhythm variables (actigraphy derived) in patients with ALL compared to healthy children.
| Patients with ALL (N = 71) mean ± SD or median [IQR] | Healthy children (N = 85) mean ± SD or median [IQR] | B(95% CI)a | p-value | |
|---|---|---|---|---|
| Interdaily stability | 0.58 ± 0.13 | 0.62 ± 0.13 | −0.07 (−0.10; −0.04) | <0.001 |
| Intradaily variability | 0.74 ± 0.24 | 0.72 ± 0.20 | 0.06 (−0.01; 0.12) | 0.070 |
| Relative amplitude | 0.92 ± 0.05 | 0.95 ± 0.03 | −0.03 (−0.04; −0.02) | <0.001 |
| L5 counts | 48.6 [36.4–72.8] | 46.3 [36.2–63.5] | 3.0 (−5.5; 11.5) | 0.485 |
| M10 counts | 1752.5 ± 758.3 | 2187.1 ± 709.3 | −599.5 (−784.2; −414.7) | <0.001 |
aAdjusted for patient age, sex, sleep medication use and highest attained parental educational level.