Table 4.

Cancer-related fatigue (PedsQL MFS scores) in patients with ALL compared to healthy children

PedsQL MFS scale	Patients with ALL mean ± SD or median [IQR]	Healthy children [33] mean ± SD or median [IQR]	B (95% CI)a	p-value
Parent reports	N = 122	N = 497
General fatigue	56.61 ± 25.51	83.33 [70.83–91.67]	−25.60 (−29.11; −22.10)	<0.001
Sleep-rest fatigue	70.83 [56.25–83.33]	87.50 [75.00–95.83]	−16.11 (−19.40; −12.82)	<0.001
Cognitive fatigue	75.00 [66.67–95.83]	79.17 [66.67–95.83]	−1.29 (−5.04; 2.47)	0.502
Self-reports	N = 33	N = 298
General fatigue	70.83 [50.00–83.33]	79.17 [70.83–91.67]	−12.86 (−18.47; −7.25)	<0.001
Sleep-rest fatigue	70.38 ± 15.99	74.60 ± 14.84	−4.59 (−10.30; 1.28)	0.115
Cognitive fatigue	75.00 [56.25–91.67]	79.17 [66.67–91.67]	−5.64 (−12.52; 1.24)	0.108

^aAdjusted for patient age, sex, sleep medication use, and highest attained parental educational level.