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. Author manuscript; available in PMC: 2021 Apr 29.
Published in final edited form as: J Am Chem Soc. 2020 Apr 16;142(17):7776–7782. doi: 10.1021/jacs.9b13186

Figure 3.

Figure 3.

Selected examples of building blocks used in strain-promoted cycloaddition reactions of DNA-conjugated allenes derived in situ from 3. Product display (%AUC) was determined by integration of UV signals (260 nm) considering DNA-species only. For additional examples of [2 + 2] reactions, see SI, Figure S5. For titration experiments with each type of cycloaddition partner, see SI, Figure S6.