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. 2020 Jun 12;48(6):0300060520925996. doi: 10.1177/0300060520925996

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© The Author(s) 2020

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — a–c: To determine the effective concentration of disulfiram, we measured the inhibition rate of different disulfiram concentrations (0, 10, 25, 50, 75, 100, and 125 μmol/L) on GES, MKN45, and SGC-7901 cells by the CCK-8 assay. The results showed that 50 μmol/L was the IC₅₀ value for disulfiram in gastric cancer cells. d–f: CCK-8 result showed that disulfiram significantly inhibited the proliferation of gastric cancer cells in vitro, and ELISA showed decreased PCNA expression.