Table 2.
Serum calcium |
iPTH |
||||||
---|---|---|---|---|---|---|---|
Normal | Low | Normal | Low | ||||
Variable | Total | (n = 343) | (n = 203) | P-value | (n = 340) | (n = 206) | P-value |
Sex | 0.960 | 0.787 | |||||
Female | 388 | 244 | 144 | 243 | 145 | ||
Male | 158 | 99 | 59 | 97 | 61 | ||
Age, years | 51.2 ± 13.6 | 50.0 ± 12.3 | 0.307 | 50.6 ± 9.9 | 51.3 ± 9.5 | 0.454 | |
Preoperative diagnosis | 0.771 | 0.709 | |||||
Thyroid nodular goiter | 123 | 78 | 45 | 75 | 48 | ||
Thyroid follicular tumor | 83 | 53 | 30 | 49 | 34 | ||
Thyroid carcinoma | 340 | 212 | 128 | 216 | 124 | ||
Surgical procedure | 0.088 | 0.266 | |||||
Total thyroidectomy plus central dissection | 316 | 189 | 127 | 190 | 126 | ||
Total thyroidectomy | 230 | 154 | 76 | 150 | 80 | ||
Preoperative laboratory data | |||||||
Calcium, mmol/L | 2.23 ± 0.09 | 2.22 ± 0.09 | 0.952 | 2.27 ± 0.08 | 2.26 ± 0.09 | 0.888 | |
25-hydroxyvitamin D3, ng/mL | 21.82 ± 8.38 | 20.94 ± 7.71 | 0.221 | 20.47 ± 8.38 | 19.19 ± 7.96 | 0.079 | |
Magnesium, mmol/L | 0.87 ± 0.07 | 0.89 ± 0.30 | 0.224 | 0.88 ± 0.31 | 0.84 ± 0.25 | 0.070 | |
Phosphate, mmol/L | 1.16 ± 0.18 | 1.13 ± 0.22 | 0.096 | 1.16 ± 0.16 | 1.13 ± 0.26 | 0.114 | |
Alkaline phosphatase, pg/mL | 73.4 ± 23.7 | 71.2 ± 21.6 | 0.256 | 62.1 ± 23.1 | 65.1 ± 18.7 | 0.111 | |
TSH, mIU/L | 1.87 ± 1.01 | 1.91 ± 0.95 | 0.653 | 1.95 ± 1.04 | 2.09 ± 1.04 | 0.147 | |
iPTH, pg/mL | 38.8 ± 11.9 | 39.4 ± 11.1 | 0.586 | 37.34 ± 15.5 | 39.07 ± 10.4 | 0.119 | |
24 hours postoperatively | |||||||
iPTH, pg/mL | 24.37 ± 10.6 | 21.23 ± 10.6 | 0.001 | 26.72 ± 8.45 | 9.07 ± 3.38 | <0.001 | |
Calcium, mmol/L | 2.16 ± 0.05 | 1.95 ± 0.05 | <0.001 | 2.10 ± 0.01 | 1.89 ± 0.12 | <0.001 |
Data are expressed as number or as mean ± standard deviation.
iPTH, intact parathyroid hormone; TSH, thyroid-stimulating hormone.
A P value of <0.05 was considered statistically significant.