Table 2.

Univariate analysis

Number of patients	185
Variables	HR (95% CI; p value)
Age(> 67 vs ≤ 67)	1.01 (0.65–1.57; p = 0.97)
Sex(male vs female)	1.35 (0.84–2.17; p = 0.22)
Site(rectum vs colon)	1.86 (1.18–2.95; p = 0.08)
Size(3/4 vs 1/2)	1.50 (0.72–3.12; p = 0.28)
Node(N+ vs N-)	1.63 (1.04–2.57 p = 0.03)
Metastasis(M+ vs M-)	2.89 (1.79–4.68; p < 0.0001)
Grading(3 vs 1/2)	1.25 (0.72–2.17; p = 0.42)
VEGF-A(L vs H)	1.58 (1.01–2.48; p = 0.046)
TRF2(L vs H)	1.13 (0.72–1.77; p = 0.60)
VEGF-A/TRF2(H/H vs others)	1.66 (1.04–2.64; p = 0.032)