Table 1.
Characteristics of enrolled patients
| Characteristics | High-risk | Low-risk | ||
|---|---|---|---|---|
| High-risk chemotherapy | High-risk HSCT | P | Total | |
| Age (years) | 9.5 ± 3.3 | 10.4 ± 4.3 | 0.036 | 8.7 ± 3.6 |
| Gender (male/female) | 14/14 | 18/9 | 0.072 | 38/32 |
| WBC (109) | 25.6 ± 19.1 | 22.7 ± 26.4 | 0.697 | 16.8 ± 15.8 |
| EI (%) | 25 | 18.5 | 0.561 | 21.4 |
| c-KIT mutation (%) | 42.8 | 33.3 | 0.094 | 27.1 |
| MRD after induction (%) | 4.2 ± 9.7 | 3.1 ± 5.1 | 0.269 | 1.9 ± 1.2 |
| MRD after the first consolidation (%) | 1.4 ± 2.9 | 2.1 ± 3.4 | 0.226 | 0.08 ± 0.14 |
| MRD after the second consolidation (%) | 0.54 ± 1.0 | 0.9 ± 1.0 | 0.365 | 0.01 ± 0.01 |
Abbreviations: EI extramedullary infiltration, HSCT hematopoietic stem cell transplantation, MRD minimal residual disease, WBC white blood cell