Figure 2.

Cube view of DEL951 analysis. Points represent enrichment of library member after 3 rounds of affinity selection using biotinylated Naa50 protein (larger size = greater enrichment). Affinity selection was performed using 250 pmol Naa50 in the presence of the AcCoA cofactor. The cube axes depict the R₁, R₂, and R₃ building blocks employed during construction of the library. R₁ building block structures which afforded enrichment of multiple library members are also shown (2a–2c). Note that the 2a building block afforded two vertical rows of enriched library members.