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. 2020 Apr 10;11(6):1175–1184. doi: 10.1021/acsmedchemlett.0c00029

Figure 6.

Figure 6

Crystal structure of the complex of 4a with Naa50 in the presence of AcCoA (1.07 Å, PDB ID 6WFN). View from the top of the binding pocket. AcCoA is drawn in pale blue stick representation while 4a is in magenta stick representation. The binding mode and hydrogen bonds (dashed lines) between 4a and Naa50 are identical to those observed in the presence of CoA.