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. 2020 Apr 13;11(6):1236–1243. doi: 10.1021/acsmedchemlett.0c00095

Figure 2.

Figure 2

Docked pose of (P)-14 in the homology model of PI3Kβ built from the cocrystal structure of (P)-19 bound to PI3Kδ (pdb: 6DGT).19 Some residues have been removed for clarity, and yellow dashed lines show hydrogen bond contacts between the inhibitor and the protein.