Figure 5.
CK isoform activities in the study groups. CK isoform activity (IU/mg protein) (A through D) and CK isoform activity relative to total CK activity (from left to right: MtCK, CK-MM, CK-MB, and CK-BB) in 1 control and 2 AS groups (E through H). *Post hoc pairwise tests significant versus NH. †Post hoc pairwise tests significant versus SevAS-pEF. AS indicates aortic stenosis; CK, creatine kinase; CK-MM, CK-MB, and CK-BB, creatine kinase MM, MB, and BB isoforms; MtCK, mitochondrial type creatine kinase isoform; NHBx, non–pressure-loaded heart biopsy; SevASpEF, severe aortic stenosis with preserved ejection fraction; and SevAS-rEF, severe aortic stenosis with reduced ejection fraction.