Table 1.
Performance measures during active/inhibitory avoidance, active avoidance, and active/inhibitory reward-seeking tasks
| PL (control) | PL (inactivation) | IL (control) | IL (inactivation) | |
|---|---|---|---|---|
| Active/inhibitory avoidance | ||||
| Active avoidance latency (s) | 5.75 ± 0.8 | 9.49 ± 1.9 | 6.11 ± 1.3 | 7.6 ± 1.1 |
| Inhibitory avoidance failure latency (s) | 9.21 ± 1.87 | 8.34 ± 2.4 | 7.6 ± 2.4 | 6.78 ± 1.1 |
| Shocks received | 8.8 ± 1.91 | 29.3 ± 2.1** | 5.5 ± 4.1 | 16.9 ± 2.9** |
| Locomotion (beam breaks/min) | 15.8 ± 1.7 | 16.8 ± 3.3 | 19.6 ± 2.0 | 29.5 ± 5.1 |
| Active avoidance | ||||
| Avoidance latency (s) | 5.04 ± 0.4 | 4.56 ± 0.5 | 5.57 ± 0.41 | 5.59 ± 0.54 |
| Shocks received | 7.3 ± 3.3 | 9.1 ± 2.7 | 6.0 ± 1.33 | 22.9 ± 4.33* |
| Locomotion (beam breaks/min) | 18.2 ± 2.6 | 25.5 ± 4.0 | 12.7 ± 1.7 | 20.1 ± 2.92 |
| Active/inhibitory reward-seeking | ||||
| Active response latency (s) | 1.01 ± 0.1 | 2.34 ± 0.6* | 1.41 ± 0.3 | 1.34 ± 0.2 |
| Inhibitory failure latency (s) | 4.64 ± 1.4 | 2.9 ± 0.6 | 3.9 ± 1.2 | 3.21 ± 0.6 |
| Rewards received | 36.7 ± 1.4 | 25.1 ± 1.2 *** | 38.4 ± 1.2 | 26 ± 0.8*** |
| Locomotion (beam breaks/min) | 18.9 ± 3.3 | 21.3 ± 4.2 | 21.1 ± 2.8 | 32.7 ± 5.4 |
Values displayed are mean ± SEM;
*p < 0.01,
**p < 0.001,
***p < 0.0001.