Table 5.
Impact of genetic variants of and various clinicopatholgical characteristics on the 5 years survival rate in uterine cervical cancer patients.
| Characteristics | 5 years survival HR | |
|---|---|---|
| p value | HR & 95% CIb | |
| GAS5 | ||
| rs145204276 | ||
| Ins/Del & Del/Del vs Ins/Insa | 0.049 | 3.45 (1.01-11.82) |
| Del/Del vs Ins/Ins & Ins/Dela | 0.162 | 0.21 (0.02-1.88) |
| rs55829688 | ||
| TC/CC vs TTa | 0.431 | 0.63 (0.20-1.97) |
| CC vs TT/TCa | 0.214 | 5.56 (0.37-82.87) |
| Pathologic type | ||
| adenocarcinoma vs squamous cell carcinomaa | 0.046 | 3.71 (1.02-13.49) |
| Pelvic lymph node | ||
| metastasis vs no metastasisa | 0.005 | 7.78 (1.85-32.62) |
Statistical analyses: Cox proportional hazard model
aAs a comparison reference
HR, hazard ratio and 95% CI, 95% confidence interval for GAS5 genetic variants and clinicopathological characteristics, compared with their respective controls.
Ins, insertion, presence of AGGCA; Del, deletion, absence of AGGCA.