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. 2020 May 18;17(9):1269–1280. doi: 10.7150/ijms.46441

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PPI network, hub genes network and modules analyses of DEGs. A, PPI network of DEGs. B, The network of 15 hub genes with a higher degree of connectivity and enrichment analysis of these genes. C, Genes of top 3 modules were performed GO and KEGG enrichment analysis by Metascape. Nodes were color-coded based on the expression of DEGs (red, upregulated; green, downregulated).Abbreviations: DEGs: differentially expressed genes; GO: Gene ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes, PPI: protein-protein interaction.