Table 2.

Top 20 GO terms enrichment analysis of DEGs by Metascape

Gene	GO	Category	Description	Count	%	Log10(P)	Log10(q)
↓↑	GO:0001501	GO BP	skeletal system development	36	14.63	-19.06	-14.71
↓	GO:0062023	GO CC	collagen-containing extracellular matrix	30	12.20	-16.60	-12.55
↓↑	GO:0001568	GO BP	blood vessel development	34	13.82	-12.31	-8.82
↓↑	GO:0051216	GO BP	cartilage development	19	7.72	-12.27	-8.82
↓	GO:0005833	GO CC	hemoglobin complex	7	3.63	-11.85	-8.34
↓	GO:0000904	GO BP	cell morphogenesis involved in differentiation	28	14.51	-10.99	-7.72
↓↑	GO:0048729	GO BP	tissue morphogenesis	28	11.38	-9.47	-6.41
↓	GO:0097435	GO BP	supramolecular fiber organization	24	12.44	-8.99	-6.14
↓	GO:0019838	GO MF	growth factor binding	12	6.22	-8.92	-6.10
↓	GO:0044420	GO CC	extracellular matrix component	9	3.66	-8.67	-5.74
↓	GO:0005788	GO CC	endoplasmic reticulum lumen	18	7.32	-8.48	-5.60
↓	GO:0050808	GO BP	synapse organization	18	9.33	-8.26	-5.52
↓↑	GO:0060536	GO BP	cartilage morphogenesis	7	2.85	-7.87	-5.16
↓	GO:0009611	GO BP	response to wounding	22	11.40	-7.50	-4.89
↓	GO:0001503	GO BP	ossification	19	7.72	-7.50	-4.85
↓	GO:0030003	GO BP	cellular cation homeostasis	21	10.88	-7.16	-4.58
↓	GO:0045177	GO CC	apical part of cell	16	8.29	-7.02	-4.46
↓	GO:0050839	GO MF	cell adhesion molecule binding	18	9.33	-6.91	-4.38
↓	GO:0070848	GO BP	response to growth factor	22	11.40	-6.89	-4.37
↓	GO:0031589	GO BP	cell-substrate adhesion	15	7.77	-6.71	-4.21

Abbreviations: ↓: downregulated genes; ↑: upregulated genes; GO: gene ontology; BP: biological processes; CC: cellular components; MF: molecular function; DEGs: differentially expressed genes