Table 3.
The KEGG pathways enrichment analysis of DEGs by DAVID
| ID | Term | Count | % | P value | Genes |
|---|---|---|---|---|---|
| hsa04151 | PI3K-Akt signaling pathway | 10 | 0.030149 | 0.056461 | PTK2, COL3A1, COL6A3, COL1A2, COL6A2, GNG11, COL1A1, LAMC1, SPP1, COL4A5 |
| hsa04512 | ECM-receptor interaction | 9 | 0.027134 | 2.95E-05 | SDC1, COL3A1, COL6A3, COL1A2, COL6A2, COL1A1, LAMC1, SPP1, COL4A5 |
| hsa04510 | Focal adhesion | 9 | 0.027134 | 0.008848 | PTK2, COL3A1, COL6A3, COL1A2, COL6A2, COL1A1, LAMC1, SPP1, COL4A5 |
| hsa04974 | Protein digestion and absorption | 8 | 0.024119 | 2.38E-04 | COL14A1, ATP1B2, COL3A1, COL6A3, COL1A2, COL6A2, COL1A1, COL4A5 |
| hsa04062 | Chemokine signaling pathway | 8 | 0.024119 | 0.01651 | CCL1, PTK2, PARD3, CCL14, ADCY2, TIAM1, GNG11, CXCL12 |
| hsa05205 | Proteoglycans in cancer | 8 | 0.024119 | 0.023575 | WNT7B, PTK2, CTTN, SDC1, TIAM1, IGF2, DCN, TIMP3 |
| hsa05144 | Malaria | 7 | 0.021104 | 6.11E-05 | GYPB, VCAM1, SDC1, GYPA, HBA2, HBA1, HBB |
| hsa04390 | Hippo signaling pathway | 7 | 0.021104 | 0.020389 | WNT7B, PARD3, FRMD6, CTGF, DLG3, TEAD1, GLI2 |
| hsa05202 | Transcriptional misregulation in cancer | 7 | 0.021104 | 0.031476 | PROM1, EYA1, PTK2, TSPAN7, PBX1, HMGA2, MLLT3 |
| hsa05146 | Amoebiasis | 6 | 0.018089 | 0.017315 | PTK2, COL3A1, COL1A2, COL1A1, LAMC1, COL4A5 |
| hsa04514 | Cell adhesion molecules (CAMs) | 6 | 0.018089 | 0.05155 | VCAM1, SDC1, PTPRM, CD34, NLGN4X, CDH5 |
| hsa04670 | Leukocyte transendothelial migration | 5 | 0.015074 | 0.08114 | VCAM1, PTK2, CXCL12, CDH5, THY1 |
| hsa05143 | African trypanosomiasis | 4 | 0.012059 | 0.011226 | VCAM1, HBA2, HBA1, HBB |
| hsa04923 | Regulation of lipolysis in adipocytes | 4 | 0.012059 | 0.045163 | ADCY2, ADRB1, FABP4, PRKG2 |
| hsa00982 | Drug metabolism - cytochrome P450 | 4 | 0.012059 | 0.072398 | FMO2, FMO3, UGT2B11, GSTT1 |
| hsa04976 | Bile secretion | 4 | 0.012059 | 0.074937 | ADCY2, ATP1B2, SLC4A4, ABCG2 |
| hsa05020 | Prion diseases | 3 | 0.009045 | 0.083993 | C7, C1QB, LAMC1 |
Abbreviations: KEGG: Kyoto Encyclopedia of Genes and Genomes; DEGs: differentially expressed genes.