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. 2020 May 15;16(12):2063–2071. doi: 10.7150/ijbs.45999

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KLF10 inhibits tumor growth and promotes apoptosis in vivo. (A) Representative pictures of MM xenografts from RPMI8226-KLF10 and RPMI8226-control. (B) Tumor growth curve revealed that KLF10 overexpression significantly inhibited tumor growth in vivo. Tumor nodules were subjected to immunohistochemical staining for Ki-67 (C) and TUNEL (D) assays and quantitative analysis. Representative immunostaining and TUNEL assays revealed that KLF10 overexpression significantly decreased the number of Ki-67 positive cells and increased the number of apoptotic cells. *P<0.05.