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. 2020 May 15;16(12):2063–2071. doi: 10.7150/ijbs.45999

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KLF10 inhibited PTTG1 transcription in MM cells. (A) Relative PTTG1 mRNA expression levels in MM and healthy donors were determined by qRT-PCR. (B) Representative Western blot analysis of PTTG1 expression in the MM and healthy donors was shown. (C) A significant inverse correlation between the KLF10 and PTTG1 was observed in MM tissues. KLF10 overexpression inhibited PTTG1 mRNA (D) and protein (E) expression in MM cells. (F) Luciferase reporter assays confirmed that KLF10 inhibited PTTG1 transcription in HEK293 cells. n = three repeats with similar results. *P<0.05, n.s: no significance.