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. 2020 May 16;16(12):2084–2093. doi: 10.7150/ijbs.44204

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Knockdown of KIF15 repressed the growth of breast cancer cells. (A-B) Knockdown efficiency of KIF15 was evaluated in MDA-MB-231 and SKBR3 cells through RT-qPCR and western blot. (C) Cell viability was measured by CCK-8 when KIF15 was inhibited. (D) Wound healing assay was utilized to measure cell migration capability after silencing KIF15. (E) Transwell experiment was conducted to test cell invasion after KIF15 depletion. (F) Flow cytometry was carried out to evaluate the influence of silencing KIF15 on cell cycle. Data displayed in all bar graphs were obtained from three or more independent experiments. ^*P < 0.05, ^**P < 0.01,^***P < 0.001 indicated data were statistically significant.