Feature	%IncMSE	IncNodePurity
Local Gmax probability	86.6814	47.9987
crRNA MFE	72.5480	69.6068
Unpaired probability	72.1078	57.5635
Local Cmin probability	56.9153	37.2137
hybridization MFE nt 15–23	54.5793	94.9857
Guide G nt probability	47.7324	29.2452
Guide CA di-nt probability	47.6241	21.4664
hybridization MFE nt 3–15	47.3083	46.7462
Guide CG di-nt probability	44.0711	11.7069
Guide AU di-nt probability	42.1128	15.6205
Guide CU di-nt probability	40.6967	16.9172
Guide A nt probability	39.7297	25.0736
Local GCmax probability	39.7236	59.0805
Local AUmin probability	38.8318	56.3599
Local Umax probability	38.7535	24.4657
Guide GG di-nt probability	38.5896	22.2621
Local Gmin probability	36.5244	19.6159
Guide UC di-nt probability	36.3043	15.2075
Guide AC di-nt probability	36.2901	14.2361
Guide C nt probability	36.0901	16.8637
Local Umin probability	35.6886	16.2571
Guide AG di-nt probability	34.9534	14.6260
Local Amin probability	34.6632	17.4928
Local Amax probability	33.6557	16.1888
Guide AA di-nt probability	33.2106	13.3830
Guide GC di-nt probability	33.0670	13.3209
Guide CC di-nt probability	32.2834	12.9797
Guide UG di-nt probability	31.9188	13.1659
Guide GU di-nt probability	31.8413	12.8934
Guide GA di-nt probability	31.3837	13.1399
Guide UA di-nt probability	30.6930	12.5052
Local Cmax probability	29.8186	14.2189
Local AUmax probability	22.4842	14.2585
Predicted correctly folded DR	8.2669	4.0679
Predicted G-quadruplex	−3.0274	0.0219