TABLE 3.

DAVID functional analysis of SIPs of similar interaction with WT SERT and SERT Ala56.

Annotation cluster	Enrichment score	Protein #	Gene name	p-value
SH3 Domain	6.51	11	Arhgap26, Arhgap32, Shank3, Srgap3, Yes1, Dlg2, Dlg4, Macf1, Sorbs1, Tjp2, Tnk2	1.0E-08
GTPase Activation	4.81	8	Agap2, Arhgap21. Arhgap23, Arhgap26, Arhgap32,Srgap3, Myo9a,Sipa1l1	3.9E-06
ATP Binding	4	19	Actr2, Abcd3, Atp9a, Agap2, Bmp2k, Yes1, Adck1, Acsl6, Camk2b, Csnk1a1, Csnk1d, Gak, Dgke, Mthfd1, Myo9a, Myo18a, Pcx, Stk39, Tnk2	1.1E-04
Guanylate Kinase/PDZ Domain Binding	3.16	4	Dlg2, Dlg4, Magi2, Tjp2	1.1E-04
Kinase Activity	2.28	11	Bmp2k, Yes1, Adck1, Camk2b, Csn1a1, Csnk1e, Gak, Dgke, Prkar2a, Stk39,Tnk2	9.0E-04