Figure 2.

Tile scans of immunohistochemically stained rat brain tissues after focal brain injury showing IA transplanted hBM-MSCs in many different cross section planes on the first, second and the third day after cell infusion. Both control hBM-MSCs as well as mRNA-ITGA4 transfected cells (red) were visible in the injured hemisphere. The Map2 antibody staining (green) was used to display the necrotic penumbra area. Most transplanted cells were observed in the core and the boundary of necrotic penumbra region. The cell nuclei were counterstained with Hoechst 33258 (blue). Scale 1mm.