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. 2020 May 17;10(15):6695–6714. doi: 10.7150/thno.45164

Figure 2.

Figure 2

Changes in the pH-sensitive particle size, zeta potential, and cellular uptake of miR-200 and/or Iri formulations at pH 7.4 and 6.5. Changes in (A) sizes, PDI, and (B) zeta potential of miR-200 and/or Iri formulations were measured using a Zetasizer at 30 min after incubation with PBS at pH 7.4 or 6.5. (C-E) Cellular uptake of daunorubicin (DNR; a probe of irinotecan) in various formulations into (C) NOK cells at pH 7.4 and SAS cells at (D) pH 7.4 and (E) 6.5 for 24 h, as detected by flow cytometry.