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. Author manuscript; available in PMC: 2021 Jun 3.
Published in final edited form as: J Am Chem Soc. 2020 May 21;142(22):10042–10049. doi: 10.1021/jacs.0c01978

Figure 3.

Figure 3.

Mechanical properties of the bcl-2 hairpin within (purple) and without (red) the 15 × 15 nm nanocage. (A) Change-in-contour-length (ΔL) and (B) unfolding force histograms of the bcl-2 hairpin inside and outside nanocage. (C) Change in the free energy of unzipping the bcl-2 hairpin within (purple) and without (red) nanocage. Solid curves depict Gaussian fittings. N and n depict the numbers of unfolding features and molecules, respectively.