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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Trends Chem. 2019 Jun 20;1(6):572–587. doi: 10.1016/j.trechm.2019.05.007

Figure 4. Reactions with Tethered Alkenes.

Figure 4.

(A) Larock’s seminal work on heterocycle synthesis using the reductive Heck reaction. (B) The asymmetric reductive Heck cyclization to form 3,3-disubstituted 2,3-dihydrobenzofurans. (C) The asymmetric reductive Heck cyclization to access 3-arylindanones. (D) The asymmetric reductive Heck cyclization to form 3,3-disubstituted oxindoles. (E) The asymmetric reductive Heck cyclization to access quaternary indanones. (F) The asymmetric reductive Heck cyclization to form quaternary tetrahydropyridines. (G) The asymmetric reductive Heck cyclization to access bicyclo[3.2.1]octanes.