Table 1.

Optimization of Directing Group for Oxidative Heck Coupling with 1,2-Dialkyl Alkenes^a

^aIsolated yields except where otherwise noted.

^bDetermined by ¹H NMR of the crude reaction using 1,3,5-trimethoxybenzene as internal standard.

^cn.r. = no reaction.

^dInseparable from 22% of two unidentifiable isomers that contain a 1,2-disubstituted internal olefin motif.

^eInseparable from 26% of two unidentifiable isomers that contain a 1,2-disubstituted internal olefin motif.

^fIsolated as a 7:1 mixture of isomers (Z:E).