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. Author manuscript; available in PMC: 2020 Jun 15.
Published in final edited form as: Neurobiol Aging. 2007 Nov 14;30(7):1125–1134. doi: 10.1016/j.neurobiolaging.2007.10.001

Figure 1.

Figure 1.

Quantification of frontal cortex synapse proteins in the oldest-old. All protein levels for individual synapse markers were established based on loading increasing concentrations of pooled homogenates of frontal cortex tissue to establish optimal amounts for quantifying synaptophysin (SYN)</P/> (A) PSD-95 (B) and for GAP-43 (C). Lines indicate either linear or logistic regression. Representative western blots of PSD-95, GAP-43 and SYN are shown for a subset of oldest-old cases used in the current study along with a protein loading control (GAPDH) (D).