. 2020 Jun 15;15(6):e0233974. doi: 10.1371/journal.pone.0233974

Table 1. Serum proteins differing between patients with a) E6/E7 mRNA -positive and -negative OPSCCs and b) p16^INK4a/DNA -positive and -negative OPSCCs.

E6/E7 mRNA+ vs mRNA- proteins
Accession	Protein name	p-value	FDR	FC (mRNA-/mRNA+)	ROC
P10643	Complement component C7	0.000677	0.058859	1.37	0.87
Q13790	Apolipoprotein F	0.000542	0.058859	0.41	0.84
p16^INK4a +/DNA+ vs p16^INK4a-/DNA-
Accession	Protein name	p-value	FDR	FC (p16^INK4a-DNA-/ p16^INK4a+ DNA+)	ROC
P10643	Complement component C7	0.000911	0.079284	1.42	0.86
Q08380	Galactin-3-Binding Protein	0.000879	0.079284	1.37	0.86

P-values were calculated using the unpaired t-test. These proteins remained significant following multiple-testing correction, with FDR set to 0.1. FC–fold change; ROC–receiver operating characteristic; abundance–average normalized abundance.

Table 1. Serum proteins differing between patients with a) E6/E7 mRNA -positive and -negative OPSCCs and b) p16INK4a/DNA -positive and -negative OPSCCs.

Table 1. Serum proteins differing between patients with a) E6/E7 mRNA -positive and -negative OPSCCs and b) p16^INK4a/DNA -positive and -negative OPSCCs.