Table 2. Univariate Analyses of Relationship Between Various Clinical Factors and Mortality (30 Events, n = 193).
| Variables | 2-year (%) | P valuea |
|---|---|---|
| Age ≥ 80 years | 20.6 | 0.378 |
| Male sex | 19.2 | 0.711 |
| Hypertension | 15.3 | < 0.001 |
| Diabetes mellitus | 18.5 | 0.660 |
| Dyslipidemia | 18.8 | 0.229 |
| Chronic renal disease on HD | 35.7 | 0.156 |
| Atrial fibrillation/flutter | 20.2 | 0.672 |
| Coronary artery disease | 28.1 | 0.420 |
| COPD | 43.4 | 0.028 |
| Cancer | 27.1 | 0.173 |
| SBP < 100 mm Hg | 59.2 | < 0.001 |
| Number of medication ≥ 6 at admission | 25.0 | 0.045 |
| Common PIMs | ||
| Benzodiazepines | 13.6 | 0.970 |
| Other than benzodiazepines | 15.4 | 0.867 |
| Sulfonylurea | 13.4 | 0.482 |
| Thiazolidinediones | 0.0 | 0.415 |
| Metformin | 16.7 | 0.806 |
| Steroid | 57.1 | 0.197 |
| NSAIDs | 39.1 | 0.002 |
| H2 antagonists | 33.9 | 0.252 |
| PPIs | 28.8 | 0.080 |
| Hb < 12 g/dL | 22.7 | 0.900 |
| Alb < 3.5 g/dL | 26.6 | 0.011 |
| eGFR < 45 mL/min/1.73 m2 | 21.5 | 0.323 |
aLog-rank test. HD: hemodialysis; COPD: chronic obstructive pulmonary disease; SBP: systolic blood pressure; PIM: potentially inappropriate medication; NSAIDs: non-steroidal anti-inflammatory drugs; PPIs: proton pump inhibitors; Hb: hemoglobin; Alb: albumin; eGFR: estimated glomerular filtration rate.