Table 2. Predictive factors for the response of IV steroid treatment by logistic regression analysis performed using backward stepwise procedures.

Variables	Univariate analysis			Multivariate analysis
	OR	95% CI	P value	OR	95% CI	P value
Age	0.947	0.902–0.955	0.030	0.918	0.856–0.985	0.017
Gender, men	0.795	0.253–2.502	0.696
Body mass index, kg/m2	1.041	0.834–1.301	0.721
Duration of GO, mon	0.991	0.957–1.026	0.612
Smoking	1.591	0.523–4.873	0.413
Sum of EOM, mm	1.020	0.905–1.148	0.749	1.163	0.973–1.389	0.096
TSH, µIU/mL	0.972	0.820–1.153	0.743
Free T4, ng/dL	0.814	0.353–1.877	0.629
Pretreatment TBII, IU/L	0.952	0.908–0.997	0.038	0.921	0.864–0.982	0.012
Changes of TBII for 12 wk	0.959	0.901–1.021	0.193
Total cholesterol, mg/dL	0.993	0.979–1.007	0.320
MRD1, mm	1.171	0.809–1.694	0.404
Proptosis, mm	1.139	0.944–1.374	0.174
Diplopia	1.360	0.458–4.042	0.580
NOSPECS Class II, ≥ b	4.846	0.540–43.464	0.159	7.204	0.544–95.386	0.134
CAS, ≥ 4	1.983	0.652–6.031	0.227

IV = intravenous, CI = confidence interval, OR = odds ratio, GO = Graves' ophthalmopathy, EOM = extraocular muscle, TSH = thyroid stimulating hormone, TBII = thyrotropin binding inhibitory immunoglobulin, MRD = margin reflex distance, CAS = clinical activity score.