Table 2:

Percent Cell Death According to Treatment Condition

Cell Line	Cell Death at 0 Gy			Cell Death at 10 Gy			Cell Death at 20 Gy
	WR-1065 Dose		P-value	WR-1065 Dose		P-value	WR-1065 Dose		P-value
	0 mM	0.25 mM		0 mM	0.25 mM		0 mM	0.25 mM
FF	18.3%	11.8%	0.15	39.3%	14.5%	0.000	52.7%	19.4%	0.01
MDA-MB-468	10.3%	11.4%	0.39	52.8%	54.6%	0.895	60.4%	63.1%	0.66
MDA-MB-231	19.6%	14.3%	0.77	50.9%	61.4%	0.408	69.8%	67.5%	0.89
MCF-7	14.4%	12.8%	0.05	42.6%	52.0%	0.102	56.4%	68.8%	0.55

There was no significant difference in cell death between breast cancer cells (MDA-MB-468, MDA-MB-231, MCF-7) treated with 0.25 mM WR-1065 prior to XRT compared to their untreated controls at 0 Gy, 10 Gy, and 20 Gy. This same dose of WR-1065 demonstrated a significant decrease in FF cell death compared to untreated FF controls at 10 Gy and 20 Gy.