Fig. 2.

Sevoflurane reduces brain glucose metabolism in young mice. a PET images illustrating local cerebral glucose metabolism in young, adult and old mice 24 h before the first exposure to sevoflurane (upper panel) and 24 h after the third exposure (lower panel). n = 4 for each group. b Representative quantification of glucose metabolism in five brain regions from three different-aged mice 24 h before the first exposure to sevoflurane. *P < 0.05 versus adult mice. c, d, e Representative quantification of glucose metabolism in five brain regions from young, adult and old mice 24 h before the first exposure to sevoflurane and 24 h after the third exposure. *P < 0.05 versus cerebral glucose metabolism in young mice 24 h before the first exposure to sevoflurane. The data are presented as the mean ± s.e.m