Fig. 3.

Sevoflurane impairs learning and memory in young mice. a Swimming tracks during the probe trial on P28. The arrow denotes the quadrant in which the escape platform was previously placed during MWM training from P23 to P27. b The average swimming speed during the probe trial on P28. c Escape latency (the time to locate the escape platform) during MWM training from P23 to P27. On P26, *P < 0.05 versus the Con group. On P27, ^#P < 0.05 versus the Con group. d Percent time spent in the target quadrant during the probe trial on P28. *P < 0.05 versus the Con group. e Tracks in the OFT. f Total ambulatory distance, time spent in the centre zone, and total faecal boli during the OFT. These are effective indicators of emotional activity in mice. g Tracks in the testing phase of the NOR test. The arrow denotes the novel object moved to a novel location in the testing phase. h RI in the testing phase of the NOR test. RI = the time devoted to the novel object/the total time devoted to the familiar and novel objects. *P < 0.05 versus the Con group. n = 12 in the Con group, n = 11 in the Sev group. The data are presented as the mean ± s.e.m