Table 2.
Quality of life assessment scores in children with Down syndrome, categorized by age
| Age | Number of patients | Physical health scores/100 (lowest-highest scores, SD) | Psychosocial health scores/100 (lowest-highest scores, SD) | Mean of all scores (lowest-highest scores, SD) | |||
|---|---|---|---|---|---|---|---|
| Physical functioning | Physical symptomatology | Emotional functioning | Social functioning | *Cognitive/school functioning | |||
| 1–12 months | 10 | 66.4 (29.1–91.6, 24.5) | 73.5 (55–90, 10.2) | 77.1 (42.1–86.6, 14.1) | 75.6 (31.2–100, 14) | 55.6 (18.7–87.5, 30.0) | 69.4 (56.1–88.3, 10.8) |
| 13–24 months | 6 | 74 (52.7–88.9, 15.2) | 72.5 (60–92.5, 14.9) | 78.1 (66.7–83.3, 7.9) | 79.7 (70–87.5, 7.2) | 35.4 (22.2–44.4, 13.9) | 66.6 (54.1–75.6, 9.6) |
| 2–4 years | 12 | 67.7 (18.8–100, 28.5) | 71.6 (45–90, 15) | 63.3 (25–100, 25.7) | 72.3 (41.7–100, 23.2) | 64.7 (32.2–86.8, 16.4) | |
| 5–7 years | 6 | 60 (40.6–81.3, 16.2) | 66.7 (45–80, 14.4) | 62.5 (30–95, 25) | 41.9 (25–62.5, 17.5) | 58.2 (31.3–75.3, 18.9) | |
| 8–12 years (proxy reporting) | 6 | 75 (34.4–100, 24.6) | 73.9 (58.3–85, 12) | 83.3 (60–100, 18.6) | 59 (30–90, 27) | 77.3 (51.1–89.7) | |
| 8–12 years (self reporting) | 4 | 74.7 (62.5–96.9, 15.8) | 77.5 (75–85, 5) | 67.5 (15–100, 40) | 65.5 (41.7–85, 18.9) | 70.8 (62.3–86.7, 11.1) | |
| Total | 44 | 69.4 (18.8–100, 20.2) | 73.6 (42.1–90, 12.8) | 71.5 (15–100, 24.3) | 57.2 (18.7–85, 25.6) | 67.9 (31.3–88.3, 14.5) | |
*Cognitive functioning is used for children under 2 years of age; school functioning for those over 2 years of age