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. 2020 Jun 15;8:21. doi: 10.1186/s40635-020-00313-3

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Time course of laboratory findings and treatment milestones during clinical application of the adsorber device after MDMA intoxication. Serum concentrations of interleukin 6 (IL-6), myoglobin, 3,4-methylenedioxymethamphetamine (MDMA), creatinine, sodium, bilirubin, and international normalized ratio (INR), fibrinogen levels, and aspartate amino transferase (AST) activity were repeatedly measured during the clinical course. MELD score (Model of End-Stage Liver Disease) was calculated to assess liver injury (a). Timeline indicating durations of mechanical ventilation (purple), external cooling (mid-blue), continuous renal replacement therapy (CRRT) with CytoSorb (light-blue), and intermittent renal replacement therapy (IRRT, dashed light-blue) (b)