Table 1.
Platforms harmonizing preclinical pharmacogenomic datasets and providing basic processing functions for biomarker discovery.
| Platforms | Cancer models | # Models | # Drugs | URL | References |
|---|---|---|---|---|---|
| PharmacoGx PharmacoDB | Cell lines | 1691 | 759 | https://bioconductor.org/packages/PharmacoGx/ http://pharmacodb.ca/ | 17,111 |
| GDSCTools | Cell lines | 1001 | 265 | https://gdsctools.readthedocs.io | 112 |
| CellminerCDB | Cell lines | ∼1000 | ~50,000 | https://discover.nci.nih.gov/cellminercdb/ | 113 |
| CancerDP | Cell lines | 1061 | 24 | http://crdd.osdd.net/raghava/cancerdp/index.php | 114 |
| PDXFinder | PDX | 567 | 33 | https://www.pdxfinder.org/ | Unpublished |
| Xeva | PDX | 277 | 61 | https://github.com/bhklab/Xeva | 115 |
| Cancer-Drug eXplorer | 2D cell cultures | 462 | 60 | http://cancerdrugexplorer.org/ | 116 |