Table 5.
Tools for visualizing, evaluating, and predicting synergistic drug combinations.
| Name | Implementation | Purpose | Features | URL |
| SynergyFinder | Web Application | Evaluating Combo Efficacy | Has 4 different drug interactivity models Computes single-agent effects Computes synergy scores | https://synergyfinder.fimm.fi/ |
| Combenefit | Desktop Application | Evaluating Combo Efficacy | Has 3 different drug interactivity models Meant to handle large batch experiments | https://www.cruk.cam.ac.uk/research-groups/jodrell-group/combenefit |
| CImbinator | Web Application | Evaluating Combo Efficacy | Has 1 drug interactivity model | http://cimbinator.bioinfo.cnio.es/CombinationIndex |
| DIGREM | Web Application | Evaluating Combo Efficacy | Models response curve and gene expression changes after treatment | http://lce.biohpc.swmed.edu/drugcombination/ |
| RACS | R Package | In-Silico Synergy Prediction | Leverages drug target networks and transcriptomic profiles | https://github.com/DrugCombination/RACS |
| DeepSynergy | Web Application | Predicts Synergy Scores | Selects novel synergistic drug combinations | http://www.bioinf.jku.at/software/DeepSynergy/ |