TABLE 2.
Minimum inhibitory concentrations (MICs) for strains and transformants harboring recombinant vectors.
|
MIC (μg/mL) |
||
| Strain and (recombinant) plasmid | Imipenem | Mero- penem |
| Acinetobacter pittii A1254 | 2 | 4 |
| A. pittii CAB009 | 32 | 64 |
| A. pittii CAB010 | 8 | 16 |
| A. pittii A1254 + pYMAb2_Hygr | 2 | 4 |
| A. pittii A1254 + pYMAb2_Hygr:OXA499 | 2 | 4 |
| A. pittii A1254 + pYMAb2_Hygr:OXA499_Pa | 16 | 64 |
| A. pittii A1254 + pYMAb2_Hygr:OXA499_P009b | 32 | 128 |
| A. pittii A1254 + pYMAb2_Hygr:OXA499_P010c | 16 | 64 |
| A. pittii A1254 + pYMAb2_Hygr:OXA826 | 2 | 8 |
| A. pittii A1254 + pYMAb2_Hygr:OXA826_Pd | 2 | 8 |
| Acinetobacter baumannii ATCC 17978 | 0.125 | 0.25 |
| A. baumannii ATCC 17978 + pYMAb2_Hygr | 0.125 | 0.5 |
| A. baumannii ATCC 17978 + pYMAb2_Hygr:OXA499 | 0.125 | 0.5 |
| A. baumannii ATCC 17978 + pYMAb2_Hygr:OXA499_P | 16 | 128 |
| A. baumannii ATCC 17978 + pYMAb2_Hygr:OXA499_P009 | 32 | 128 |
| A. baumannii ATCC 17978 + pYMAb2_Hygr:OXA499_P010 | 32 | 128 |
| A. baumannii ATCC 17978 + pYMAb2_Hygr:OXA826 | 0.25 | 0.25 |
| A. baumannii ATCC 17978 + pYMAb2_Hygr:OXA826_P | 0.25 | 0.25 |
| A. pittii LMG 1035 | 0.06 | 0.25 |
| A. pittii LMG 1035 + pYMAb2_Hygr | 0.125 | 0.125 |
| A. pittii LMG 1035 + pYMAb2_Hygr:OXA499 | 0.125 | 0.25 |
| A. pittii LMG 1035 + pYMAb2_Hygr:OXA499_P | 16 | 64 |
| A. pittii LMG 1035 + pYMAb2_Hygr:OXA499_P009 | 64 | 128 |
| A. pittii LMG 1035 + pYMAb2_Hygr:OXA499_P010 | 16 | 64 |
| A. pittii LMG 1035 + pYMAb2_Hygr:OXA826 | 0.125 | 0.25 |
| A. pittii LMG 1035 + pYMAb2_Hygr:OXA826_P | 0.125 | 0.25 |
aOXA499_P indicates blaOXA–499 with its natural promoter cloned from A1254. bOXA499_P009 indicates blaOXA–499 with its mutated promoter cloned from CAB009. cOXA499_P010 indicates blaOXA–499 with its mutated promoter cloned from CAB010. dOXA826_P indicates blaOXA–826 with its natural promoter cloned from A1254.