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. 2020 Jun 9;11:1067. doi: 10.3389/fmicb.2020.01067

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Copyright © 2020 Jiang, Wu, Jiang, Xie, Bu, Liu, Zhang and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clinical symptoms and histopathological analysis of organs in the PCV3-inoculated KM mice. (A) Mouse tissue anatomy. There were no noticeable differences between KM mice inoculated with PCV3 and normal KM mice in the morphology of tissue changes. (B) Tissue section results. The heart, liver, spleen, lung and kidney sections from no PCV3-inoculated KM mice exhibited normal morphology. Lung lesions from PCV3-inoculated KM mice showed local alveolar wall vascular dilatation and interstitial pneumonia, and no significant changes in other tissues.