Table 2.
Predictors of infarct growth and any hemorrhagic transformation in univariate and multivariate analyses.
|
crude OR [95% CI] |
p-value |
adjusted OR [95% CI] |
p-value | |
|---|---|---|---|---|
| Infarct growth | ||||
| High vs low MMP-9 level at H6 | 1.93 (0.92–4.01) |
0.08 | 3.43 (1.23–9.55) |
0.02 |
| Glucose level1 | 1.25 (1.02–1.54) |
0.03 | 1.43 (1.08–1.90) |
0.01 |
| Temperature2 | 1.78 (0.93–3.41) |
0.08 | 2.55 (1.03–6.29) |
0.04 |
| Reperfusion (TICI 2b-3) |
0.27 (0.09–0.79) |
0.02 | 0.16 (0.03–0.77) |
0.02 |
| Any hemorrhagic transformation | ||||
| High vs. low MMP-9 level at H6 | 2.48 (1.16–5.27) |
0.02 | 2.91 (1.14–7.42) |
0.03 |
| Glucose level1 | 1.10 (0.97–1.24) |
0.14 | 1.20 (1.02–1.42) |
0.03 |
| Onset to groin puncture time3 | 1.04 (1.00–1.09) |
0.06 | 1.08 (1.02–1.14) |
0.01 |
OR, odds ratio; MMP-9, matrix metalloproteinase 9; H6, hour 6; IV, intravenous; TICI, thrombolysis in cerebral infarction score; ICA, internal carotid artery.
1
per 1 mmol/L increase.
2
per 1°C increase.
3
per 30 min increase.
Significant values are shown in bold.