Table 3.
Summary of Glucose Metrics by Daytime and Nighttime (n = 153)
| All Participants | Age Group | |||||
|---|---|---|---|---|---|---|
| 6 to <12 y | 12 to <18 y | 18 to <25 y | 25 to <60 y | ≥60 y | ||
| N | 153 | 27 | 30 | 29 | 41 | 26 |
| Daytime (6:00 am to 11:59 pm) | ||||||
| CGM use, h (mean ± SD) [range] | 142 ± 24 | 133 ± 27 | 133 ± 21 | 143 ± 21 | 154 ± 18 | 145 ± 26 |
| [54–179] | [54–173] | [87 to 173] | [68–169] | [104–179] | [96–176] | |
| Overall glucose distribution and variability | ||||||
| Mean, mg/dL (mean ± SD) | 100 ± 7 | 99 ± 6 | 99 ± 6 | 99 ± 6 | 100 ± 6 | 104 ± 9 |
| SD, mg/dL (mean ± SD) | 17 ± 3 | 17 ± 2 | 15 ± 3 | 19 ± 3 | 17 ± 3 | 19 ± 5 |
| CV, % (mean ± SD) | 17 ± 3 | 17 ± 3 | 16 ± 2 | 19 ± 3 | 17 ± 3 | 18 ± 4 |
| Percentage of glucose sensor values, median (IQR) | ||||||
| >180 mg/dL | 0.0 (0.0–0.2) | 0.0 (0.0–0.2) | 0.0 (0.0–0.0) | 0.0 (0.0–0.5) | 0.0 (0.0–0.2) | 0.2 (0.0–0.3) |
| >160 mg/dL | 0.4 (0.1–1.1) | 0.3 (0.1–0.8) | 0.2 (0.0–0.3) | 0.6 (0.2–1.5) | 0.5 (0.2–1.1) | 0.7 (0.1–3.0) |
| >140 mg/dL | 2.4 (1.2–4.5) | 2.1 (1.0–3.4) | 1.4 (0.4–2.2) | 3.0 (1.6–5.1) | 2.7 (1.5–3.8) | 5.2 (1.6–9.0) |
| 70–140 mg/dL | 96 (92–97) | 96 (94–97) | 97 (95–98) | 95 (91–96) | 96 (93–97) | 92 (88–97) |
| 70–120 mg/dL | 87 (80–91) | 87 (81–91) | 90 (84–92) | 86 (81–89) | 87 (84–90) | 78 (70–87) |
| <70 mg/dL | 1.4 (0.4–2.7) | 0.9 (0.5–2.8) | 1.4 (0.6–2.4) | 1.4 (0.5–4.9) | 1.3 (0.3–2.5) | 1.4 (0.3–3.6) |
| <60 mg/dL | 0.2 (0.0–0.5) | 0.2 (0.0–0.4) | 0.2 (0.0–0.4) | 0.2 (0.0–0.7) | 0.2 (0.0–0.4) | 0.2 (0.0–0.6) |
| <54 mg/dL | 0.0 (0.0–0.2) | 0.0 (0.0–0.1) | 0.0 (0.0–0.2) | 0.0 (0.0–0.4) | 0.0 (0.0–0.2) | 0.0 (0.0–0.1) |
| Percentage of participants with ≥1 hypoglycemic eventa | 18 | 4 | 13 | 31 | 20 | 19 |
| Duration of hypoglycemic events for participants with ≥1 hypoglycemic event, mina,b | ||||||
| n | 37 | 1 | 4 | 14 | 10 | 8 |
| Median (IQR) | 60 (45–100) | 165 | 63 (40–120) | 53 (45–75) | 83 (35–100) | 78 (52–117) |
| Nighttime (12:00 am to 5:59 am) | ||||||
| CGM use, h (mean ± SD) [range] | 50 ± 8 | 48 ± 9 | 48 ± 8 | 49 ± 8 | 53 ± 8 | 50 ± 8 |
| [24–66] | [27–60] | [24–60] | [24–60] | [30–66] | [26–60] | |
| Overall glucose distribution and variability | ||||||
| Mean, mg/dL (mean ± SD) | 98 ± 9 | 96 ± 10 | 96 ± 8 | 97 ± 7 | 98 ± 8 | 103 ± 12 |
| SD, mg/dL (mean ± SD) | 12 ± 4 | 12 ± 4 | 11 ± 2 | 14 ± 4 | 11 ± 4 | 13 ± 5 |
| CV, % (mean ± SD) | 13 ± 4 | 12 ± 4 | 12 ± 2 | 15 ± 4 | 12 ± 4 | 12 ± 4 |
| Percentage of glucose sensor values median (IQR) | ||||||
| >180 mg/dL | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) |
| >160 mg/dL | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.0) | 0.0 (0.0–0.3) |
| >140 mg/dL | 0.0 (0.0–1.0) | 0.0 (0.0–0.6) | 0.0 (0.0–0.6) | 0.6 (0.0–2.4) | 0.0 (0.0–0.9) | 0.0 (0.0–2.5) |
| 70–140 mg/dL | 99 (95–100) | 99 (96–100) | 98 (96–100) | 97 (93–99) | 99 (98–100) | 98 (94–100) |
| 70–120 mg/dL | 94 (88–97) | 95 (89–98) | 95 (91–97) | 91 (87–94) | 96 (87–98) | 92 (84–96) |
| <70 mg/dL | 0.4 (0.0–2.5) | 0.3 (0.0–2.3) | 0.9 (0.0–3.2) | 0.9 (0.0–3.1) | 0.4 (0.0–1.2) | 0.4 (0.0–2.4) |
| <60 mg/dL | 0.0 (0.0–0.6) | 0.0 (0.0–0.6) | 0.1 (0.0–1.0) | 0.0 (0.0–0.8) | 0.0 (0.0–0.3) | 0.0 (0.0–0.6) |
| <54 mg/dL | 0.0 (0.0–0.3) | 0.0 (0.0–0.3) | 0.0 (0.0–0.5) | 0.0 (0.0–0.3) | 0.0 (0.0–0.0) | 0.0 (0.0–0.3) |
| Percentage of participants with ≥1 hypoglycemic eventa | 14 | 19 | 20 | 17 | 7 | 8 |
| Duration of hypoglycemic events for participants with ≥1 hypoglycemic event (min)a,b | ||||||
| n | 33 | 8 | 6 | 9 | 7 | 3 |
| Median (IQR) | 50 (40–85) | 52 (33–152) | 52 (35–85) | 45 (40–75) | 55 (40–120) | 80 (40–125) |
a
A hypo event is defined as at least two sensor values <54 mg/dL that are ≥15 min apart with no intervening values >54 mg/dL. At least two sensor values >70 mg/dL that are ≥15 min apart with no intervening values <70 mg/dL are required to end a hypo event
b
Based on an event level.