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. 2020 Jun 9;11:369. doi: 10.3389/fneur.2020.00369

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Copyright © 2020 Moreira da Silva, Cowie, Blamire, Forsyth and Taylor.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect on local disassortativity by changes in regions' strength. (A,B) indicate some possible mechanisms of local disassortativity change. (A) Local disassortativity of the red region decreases when the strength differences between red regions and its neighboring regions is reduced. This reduction may occur by strengthening or weakening of internal connections. When disassortativity decreases, the red region is more assortative. (B) Similarly, local disassortativity decreases with peripheral weakening or peripheral strengthening. When the red region is connected to other regions with lower strength, disassortativity may decrease by strengthening of its low-strength neighbors. However, when connected to regions with higher strength, strengthening of those neighbors will increase disassortativity. (C) Examples on how to calculate local disassortativity for regions colored in red.