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Biological properties of cIL-10 and HCMV vIL-10.
| Gene expression (kinetics) | STAT3 activation | Cytokine inhibition | MHC inhibition | |
|---|---|---|---|---|
| cmvIL-10 (A) | Lytic infection (γ) | Yes | Yes | Yes |
| LAcmvIL-10 (B) | Lytic infection (β) Latent infection |
No | No | Yes |
| C | ? | No | ? | ? |
| D | ? | No | ? | ? |
| E | ? | No | ? | ? |
| F | ? | No | ? | ? |
| G | ? | No | ? | ? |
| cIL-10 | NA## | Yes | Yes | Yes |
?, not known;
NA, not applicable.
