Skip to main content
. 2020 Jun 9;8:585. doi: 10.3389/fbioe.2020.00585

Figure 1.

Figure 1

Simplified carbon metabolic profile of the producing Escherichia coli strain. The heterologous genes gps and crtEBIY were integrated into the E. coli genome at the ldhA locus to introduce the β-carotene pathway (Li et al., 2015). The genetic manipulations in this study are shown in colored fonts, where red represents gene deletion and blue represents gene overexpression. The multiple arrows represent multiple reactions. G6P, glucose-6-phosphate; F6P, fructose-6-phosphate; F1,6P, fructose-1,6-bisphosphate; G-l-6P, gluconolactone-6-phosphate; G3P, glyceraldehyde-3-phosphate; PEP, phosphoenolpyruvate; PYR, pyruvate; 6PG, 6-phosphogluconate; Ru5P, ribose-5-phosphate; 2-KG, 2-ketoglutaric acid; Glu, glutamic acid; DXP, 1-deoxy-d-xylulose-5-phosphate; MEP, 2C-methyl-d-erythritol-4-phosphate; CDP-ME, 4-diphosphocytidyl-2C-methyl-d-erythritol; CDP-MEP, 4-diphosphocytidyl-2C-methyl-d-erythritol-2-phosphate; MEC, 2C-methyl-d-erythritol-2,4-cyclodiphosphate; HMBPP, 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate; IPP, isopentenyl diphosphate; DMAPP, dimethylallyl diphosphate; GPP, geranyl diphosphate; FPP, farnesyl diphosphate; GGPP, geranylgeranyl diphosphate.