Table 5.

Results of association analysis between epigenetic measurements and continuous clinical data related to phenotypes in FM cohort, correcting for chronological age.

Clinical variable	Epigenetic variable	Coefficient	P-value	P-value LocAdjBH	P-value GlobAdjBH
BPI_interference	DNAmLeptin	−239.733	0.006	0.851	0.757
VAS	DNAmLeptin	−327.578	0.013	0.851	0.942
MPQ_evaluative	DNAmTL	−0.183	0.013	0.851	0.942
BPI_interference	CD8T	−0.002	0.016	0.851	0.942
Duration of painful symptoms	DNAmTL	0.022	0.034	0.992	0.942
PCS	NK	−0.001	0.048	0.992	0.942

Only the associations with significant nominal p-values are reported. The columns report the value of the regression coefficient (“Coefficient”), the corresponding nominal p-value (“P-value”), the p-value corrected with Benjamini–Hochberg procedure for multiple tests locally—within a single cohort (“P-value LocAdjBH”), and globally—within all the cohorts included in the study (“P-value GlobAdjBH”).