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. 2020 May 21;24:485–494. doi: 10.1016/j.jare.2020.05.020

Fig. 3.

Fig. 3

Fig. 3

Unsupervised hierarchical clustering and heatmaps of the identified SNPs in linkage disequilibrium with FGF21 rs838133 and rs838145 (columns) across different subpopulations (columns). Cells are color-coded according to the log10 of p-value, which tests the enrichment/depletion of an effect allele in a population, compared with the average of all. The red color represents allele enrichment, and the blue represents allele depletion. Cluster dendrograms are added as supplementary figures. (A) Heatmap of FGF21 rs838133 and SNPs in linkage disequilibrium (B) Heatmap of FGF21 rs838145 and SNPs in linkage disequilibrium. CEU: Utah Residents (CEPH) with Northern and Western European Ancestry (n = 99) CHS: Southern Han Chinese (n = 105) CHB: Han Chinese in Bijing, China (n = 103), BEB: Bengali from Bangladesh (n = 86), IBS: Iberian Population in Spain (n = 107), ITU: Indian Telugu from the UK (n = 102), STU: Sri Lankan Tamil from the UK (n = 102), PJL: Punjabi from Lahore, Pakistan (n = 96), GIH: Gujarati Indian from Houston, Texas (n = 103). No data were available on CHS data for rs838145 in the 1000Genome database.