Table 3.
Echocardiography Parameters in Controls and in Women With srPCOS According to the Presence of Hypertension
| Characteristic | Normotensive Control (n = 89–121) | Normotensive srPCOS (n = 10–16) | P Value a | Hypertensive Control (n = 90–146) | Hypertensive srPCOS (n = 14–21) | P Value b | P Value c | P Value d |
|---|---|---|---|---|---|---|---|---|
| LVEF biplane, % | 61.77 ± 5.42 | 62.20 ± 4.95 | 0.760 | 61.33 ± 6.27 | 59.42 ± 4.59 | 0.204 | 0.077 | 0.559 |
| Global strain | −22.38 ± 2.26 | −21.25 ± 2.43 | 0.138 | −20.82 ± 2.16 | −20.51 ± 1.74 | 0.604 | 0.004 | <0.001 |
| IVSd, cm | 0.84 ± 0.15 | 0.89 ± 0.12 | 0.165 | 0.91 ± 0.16 | 0.92 ± 0.15 | 0.669 | 0.019 | <0.001 |
| LVIDd, cm | 4.95 ± 0.45 | 4.82 ± 0.30 | 0.283 | 5.03 ± 0.49 | 5.15 ± 0.42 | 0.311 | 0.066 | 0.160 |
| LAESV, mL | 49.98 ± 13.26 | 48.67 ± 14.10 | 0.713 | 51.83 ± 16.98 | 57.81 ± 15.48 | 0.160 | 0.024 | 0.345 |
| LVMI | 139.70 ± 31.88 | 141.79 ± 25.47 | 0.801 | 162.79 ± 39.87 | 170.24 ± 32.46 | 0.426 | <0.001 | <0.001 |
| E/e′ (septal E′) | 6.94 ± 1.29 | 6.69 ± 1.06 | 0.457 | 8.00 ± 1.77 | 7.66 ± 1.63 | 0.404 | 0.024 | <0.001 |
| e′ septal mitral annulus | 0.13 ± 0.02 | 0.13 ± 0.02 | 0.863 | 0.11 ± 0.02 | 0.12 ± 0.02 | 0.203 | 0.044 | <0.001 |
| e′ lateral mitral annulus | 0.15 ± 0.03 | 0.14 ± 0.03 | 0.275 | 0.13 ± 0.03 | 0.14 ± 0.03 | 0.098 | 0.008 | <0.001 |
Data are presented as mean ± SD. Differences between groups were analyzed by the Student t test, as the data were normally distributed. Number of study participants in each group is shown in parentheses. Normotensive: Normal BP (systolic BP <130 mm Hg and diastolic BP <85 mm Hg) at ages 31 and 46 years and no antihypertensive medication at age 31 or 46 years. Hypertensive: Elevated BP (systolic BP ≥130 mm Hg and/or diastolic BP ≥85 mm Hg) at age 31 or 46 years or antihypertensive medication at age 31 or 46 years. Significant P values appear in boldface type.
Abbreviations: IVSd, interventricular septal end-diastole; LAESV, left atrium end-systolic volume; LVEF, left ventricular ejection fraction; LVIDd, left ventricular internal diameter end-diastole; LVMI, left ventricle mass index.
Comparison between normotensive PCOS and normotensive control groups.
Comparison between hypertensive PCOS and hypertensive control groups.
Comparison between hypertensive PCOS and normotensive control groups.
Comparison between hypertensive and normotensive control groups.