Table 2.

Predictors of all-cause mortality across etiology categories-results of separate COX analysis.

ICM					NICM
Variables	Univariable	P	Multivariable	P	Variables	Univariable	P	Multivariable	P
	HR(95%CI)		HR (95%CI)			HR (95%CI)		HR (95%CI)
Age (years)	1.039 (1.019–1.059)	<0.0001	1.036 (1.014–1.059)	0.001	Age (years)	1.024 (1.010–1.040)	0.001
Advanced NYHA class III-IV	2.931 (1.610–5.335)	<0.0001			SBP (mmHg)	0.989 (0.979–0.998)	0.020
Previous HF hospitalization	1.803 (1.227–2.648)	0.003	1.664 (1.120–2.473)	0.012	Advanced NYHA class III-IV	4.593 (1.864–11.316)	0.001	2.603 (0.999–6.782)	0.05
Revascularization	0.596 (0.410–0.866)	0.007			Previous HF hospitalization	3.115 (1.896–5.118)	<0.0001	1.834 (1.010–3.329)	0.046
Diabetes mellitus	1.474 (1.015–2.139)	0.041	1.776 (1.180–2.673)	0.006	Af/AFL
LVEF	0.977 (0.953–1.002)	0.070	0.968 (0.944–0.993)	0.014	Paroxysmal	3.314 (1.763–6.227)	<0.0001	2.124 (1.000–4.509)	0.05
eGFR	0.983 (0.976–0.989)	<0.0001	0.987 (0.979–0.994)	0.001	Persistent	1.467 (0.927–2.319)	0.101
Na+ (mmol/l)	0.952 (0.910–0.995)	0.030			Frequent PVB	1.583 (1.029–2.433)	0.036
Hemoglobin (g/l)	0.990 (0.981–0.999)	0.024			Non-sustained VT	1.655 (1.090–2.512)	0.018
Low T3 syndrome	2.093 (1.141–3.841)	0.017			Hypertension	0.619 (0.394–0.973)	0.038
Diuretics	1.951 (1.131–3.365)	0.016			COPD	2.808 (1.491–5.286)	0.001
Beta-blocker	0.619 (0.396–0.966)	0.035			LVEF	0.990 (0.963–1.018)	0.469
ACEI/ARB	0.605 (0.407–0.900)	0.013			eGFR	0.989 (0.982–0.996)	0.002
					Hemoglobin (g/l)	0.986 (0.976–0.996)	0.005
					Low T3 syndrome	3.737 (1.912–7.303)	<0.0001
					Beta-blocker	0.300 (0.179–0.503)	<0.0001	0.395 (0.195–0.799)	0.01
					ACEI/ARB	0.438 (0.271–0.707)	0.001
					Digoxin	1.658 (1.096–2.508)	0.017
					Isosorbide mononitrate	1.930 (1.222–3.049)	0.005	1.872 (1.109–3.162)	0.019

Note: the MDRD formula calculated eGFR = 186∗(Scr)-1.154∗(age)-0.203∗(0.742 female). eGFR was the estimated glomerular filtration rate. Scr was serum creatinine in mg/dl. Age is measured in years.